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Does the type of collagen impact its ability to be absorbed?

  • Hydrolysed collagen is a form of collagen that has undergone enzymatic hydrolysis to reduce its’ gelling properties to enable it to be easily mixed with water, and ingested.11 Meanwhile, specific collagen peptide formulations have been developed to optimise the amount of di and tri AA peptides of hydroxyproline with different molecular weights. Such formulations are claimed to have increased bioavailability,and exert additional biological functions specific to the target tissues.12-15 However, it should be noted that there does not appear to be significant differences in the bioavailability of key AAs after the consumption of different forms of collagen.16
  • The consumption of collagen results in a transient increase of circulating NEAA within the blood, peaking between 40-60 minutes after consumption.16, 17 However, there appears to be some individual variability with the availability of AAs after the consumption of collagen protein. Variability in amino acid appearance between subjects and interventions likely influenced by body weight, and possible polymorphisms of transporters and enzymes, which is potentially linked to habitual dietary intake of collagen sources.18 Further research is required to determine these individual factors.

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